招聘骨骼和关节等疾病领域人才（药理和临床药理学）

公司背景：

公司专注于骨骼、关节和肌肉重症疾病领域的全球首创新药研发；

公司的人才团队与研发管线得到了国际知名基金的高度认可项目在临床阶段。

Position 1: Pharmacologist，TS-non-clinical pharmacology

JOB RESPONSIBILITIES:

1. Designing, planning, and independently performing in-vivo experiments using small and larger animal models to dissect complex molecular phenotypes associated with human disease findings in musculoskeletal disease field.

2. Independently analyzing molecular and functional characterization of disease variants associated with disease phenotypes.

3. Designing and testing the biology of novel molecules in specific in-vitro and/or ex-vivo cell-based systems.

4. Preparing and presenting study reports and data analyses.

5. Writing regulatory documents in supporting drug development.

6. Preparing manuscripts for scientific publications.

7. Collaborating with cross functional teams across the company as well as external CROs that support the drug development pipeline.

8. Supervise and train laboratory associates.

QUALIFICATIONS:

1. PhD or equivalent degree in the field of biomedical science (biochemistry, physiology, and pharmacology, sports medicine, etc.) and a minimum of 5 years of research experience in musculoskeletal disease area with good track record of scientific presentations and publications.

2. Demonstrated experience in in vivo studies, proficient with microscopy/histology tissue process and analysis.

3. Hands-on experience in molecular and cellular biology techniques including QPCR, Western Blot, cell culture, ELISA, and more.

4. Healthy work habits and possess the ability to work in a team.

5. Fluency in English and Chinese with excellent communication and presentation skills.

6. Present a mature and stable trait and passionate about science, excellent problem solving abilities and science results driven.

7. Good management skills can excel in a fast-track environment while requiring multitask across multiple projects.

Position 2: Clinical Pharmacologist, Senior manager to Associate Director

JOB RESPONSIBILITIES:

1. Provide Clinical Pharmacology support for drug candidates from preclinical to all phases of clinical investigation.

2. Write and review relevant sections of study protocols, study reports, Investigator Brochures, IND filings and NDA/BLA submissions, ensuring that designs and documents meet regulatory and compliance requirements and project timelines.

3. Independently conduct hands-on PK and PD data analyses, including NCA, population PK/PD, and exposure-safety analyses, to support project needs.

4. Select and manage PK and PK/PD vendors conducting NCA, population PK/PD and exposure-response analyses in support of regulatory submissions.

5. Summarize and communicate study PK and PK/PD data to internal project teams and senior management.

QUALIFICATIONS：

1. Major in Pharmacy/Biomedical-related fields, master's degree or above.

2. More than 5 years working experience in clinical pharmacology.

3. Hands-on experience on PK and PK-PD software, including WinNonlin, NONMEM etc.

4. Good communication and coordination skills and can use English as the communication language for emails and meeting discussions.

5. Independent problem-solving skills and good teamwork spirit