【Live】A Series of Webinar on Nanomaterials and Applications
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Please join the webinars at the following link: koushare.com/topicIndex/i/nanomaterials-applicationsA Series of Webinar on Nanomaterials ...
Speakers：Sherri A. McFarland、Wei ChenTime in Beijing: May 30, Sunday, 9:00-10:00 AM
Time in Dallas: May 29, Saturday, 8:00-9:00 PM
Sponsors：Nanomaterials MDPI、KouShareWelcome to A Series of Webinar on Nanomaterials and Applications
We would like to invite all the Scientific Community to participate in a Series of Webinar on Nanomaterials and Applications from April to July 2021, which is sponsored by MDPI Nanomaterials and propagated by Koushare. The Webinars were scheduled at the last weekend of each month from April to July 2021 for the convenience of audiences and the speakers. Aim and ScopeThis series of Webinars are mainly designed to offer diverse sessions that address the Theme of ‘Nanomaterials and their applications’ for the purpose of sharing new thoughts and new advances among the experts, industrialists and understudies from look into topics of Nanomaterials to share their on-going developments and applications for Better tomorrow. The scope of the webinar series is to support global research communities by empowering clusters of Professor, Scientists, Researchers, Students and Business Delegates to meet and discuss topics of Nanomaterials with frontrunners in the field. These webinars cover diverse top-ranked specialties and budding aspects of important and relatively broad subject areas including nanomaterials design and synthesis for cancer detection, drug delivery, therapeutics, sensing and safety as well as security for our better life tomorrow. The talks are aimed for public with lay languages and are open to everyone in the world!
Sincerely yours
Wei Chen, Ph.D, ProfessorDepartment of PhysicsThe University of Texas at ArlingtonArlington, Texas, USA
Special website：koushare.com/topicIndex/i/nanomaterials-application
01
Tackling Cancer and Infection with Light-Responsive Molecules
Abstract
Photomedicine is an interdisciplinary field where chemistry and light meet to fight disease. Photodynamic therapy (PDT) is a special branch of photomedicine that employs a sensitizer molecule, light, and oxygen to destroy unwanted cells with spatiotemporal selectivity. Despite its enormous potential for treating certain diseases, including cancer and infection, PDT has yet to become mainstream. For over a decade, our research team has worked to bring new PDT technologies from bench to bedside. Using a multidisciplinary approach, we have introduced both synthetic compounds and natural products (both have successfully completed Phase 1 clinical trials and are currently in Phase 2) as alternatives to existing porphyrin-based PDT agents for specific indications. This seminar will share some of our experiences in developing metallodrug photosensitizers for treating bladder cancer and photoactive plant extracts for improving oral health.
Brief introduction
Dr. Sherri A. McFarland is a professor in the Department of Chemistry and Biochemistry at the University of Texas at Arlington. She is experienced in synthetic and medicinal inorganic chemistry, luminescence/diagnostics, photophysics/ photochemistry, biological chemistry, photodynamic therapy (PDT)/photochemotherapy(PCT)/photothermal therapy (PTT), and melanoma (as well as a few other cancers). Her research group designed and advanced the first metallodrug photosensitizer of its class to human clinical trials, a ruthenium (Ru) PDT agent (TLD1433) that is now in Phase 2 studies (ClinicalTrials.gov Identifiers: NCT03945162) for treating bladder cancer. She also founded a biotech start-up (Photodynamic, Inc.) to commercialize a natural product plant extract as a photoactive antimicrobial for orthodontics, which is also in a Phase 2 human clinical trial. These accomplishments and others are highlighted in 2 completed and 2 current human clinical trials, 5 issued US patents that are currently maintained in a variety of countries, 3 pending patents, 2 license agreements with industry, 2 trademarks owned by industry, 62 academic peer-reviewed publications, the first Ru PDT agent in clinical trials, and the first natural product extract photosensitizer in human clinical trials.
02
New Developments in Photodynamic Therapy – Deeper and Better
Abstract
Photodynamic therapy is a combination of light and sensitizers for cancer treatment. The sensitizers and the light are non-toxic but when they interact each other toxins like reactive oxygen species are generated that can kill cancer cells. Photodynamic therapy has the beauty of targeting tumors by the sensitizers themselves and the light, so its side-effect is much lower than chemotherapy or radiotherapy. However, the need of light for activation has some limitations as light cannot penetrate deeply into tissue, so photodynamic therapy has been widely used for skin disease treatment but not for deep cancer treatment. In this webinar, I will discuss the possible solutions for developing photodynamic therapy for deep cancer treatment and some new progress in Photodynamic therapy and the invention of new sensitizers that can be activated by UV, X-ray, microwave and ultrasound to produce reactive oxygen species for deep cancer treatment as well as immunity enhancement. New ideas for the combination of photodynamic therapy and radiation to overcome radiation resistance will be discussed.
Brief introduction
Dr. Wei Chen is a professor at the department of Physics, UT Arlington. He has been engaged in cutting-edge nanotechnology research for many years and is an internationally renowned expert in nanomedicine and cancer nanotechnology. He is well known for his inventions in cancer nano-targeted therapy and deep cancer photodynamic therapy. Currently he has published 295 papers in famous academic journals such as PNAS, Nano Letters, Signal Transduction and Targeted Therapy(Nature), Advanced Materials, Advanced Functional Materials, Materials Today Physics, presided over the compilation of 1 monograph (three volumes), and participated in the compilation of 13 monographs. His papers have been cited more than 11460 times, and his H index is 56, including one paper with 685 citations, 13 papers with more than 200 times, 28 papers with more than 100 times. He has 20 US patents granted and he has been funded with more 30 scientific research projects with a total funding of more than 9 million U.S. dollars. His early pioneering work on thermoluminescence of nanoparticles were adopted by Charles P. Poole Jr. and Frank J. Owens in their first Textbook ‘Introduction to Nanotechnology’ published in 2003. Dr. Chen's scientific research work has attracted wide attention and has been reported by the American TV program CBS. Dr. Chen received the University distinguished record of research and creative activity award in 2020. He is one of the 35 scientists from the country to be included in the National Academy of Inventors 2020 class of Senior Members. He was elected be a Fellow of the International Association of Advanced Materials (Sweden) and a Vebleo Fellow in 2020 and a Sigma Xi full member in 2021.
Nanomaterials (ISSN 2079-4991; CODEN: NANOKO) is an international peer-reviewed open access journal published monthly online by MDPI.
Text editor：Miaomiao Su
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